0.1 mg/mL conc administered as slow IV infusion over 2-6 hr. Initially 0.25 mg/kg daily over 2-6 hr. Patient w/ good cardiopulmonary function & tolerance w/o severe reaction Initially 0.3 mg/kg daily. Impaired cardiopulmonary function or severe reaction Smaller initial dose of 5-10 mg daily. May be increased gradually by 5-10 mg daily to 0.5-0.7 mg/kg daily. Max total daily dose: 1.5 mg/kg. Treatment duration: 6-12 wk or longer.
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